Journal: Indian Journal of Endocrinology and Metabolism
Article Title: Elucidating the Prognostic Role of BRAF V600E and the Activation Status of the Downstream MAPK Pathway in PTC: A Study from a Tertiary Centre in India
doi: 10.4103/ijem.ijem_235_23
Figure Lengend Snippet: (a) Chromatogram: BRAF V600E -mutated PTC. (b) PTC scored 8 for VE1; FA (inset) scored 6 (400×). (c) ROC curve: BRAF V600E IHC. (d) PTC: pMEK1/2 IHC score III (400×). (e) NIFTP: patchy pERK1/2 immunopositivity (400×). (f) DFS curves: BRAF V600E -mutated and BRAF V600E -wt cases
Article Snippet: Five-micron-thick formalin-fixed paraffin-embedded representative sections were stained for BRAF V600E (clone VE1, 1:50; Spring Bioscience) by using the Ventana automated immunohistochemical stainer according to the manufacturer’s specifications (Ventana Medical Systems, Tucson, AZ).
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